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Located close to the Border, in the Otay Mesa Industrial Business Park and 1 mile from Tijuana, Mexico, this hotel offers comfortable guest rooms with free WiFi. Guest rooms at Holiday Inn Express San Diego - Otay Mesa feature flat-screen TVs, an in-room coffee machine, a refrigerator and a microwave. Holiday Inn Express San Diego - Otay Mesa provides guests with a free hot breakfast every morning. Guests can relax and enjoy the hotel's outdoor pool or workout in the on-site fitness center. Otay Lake City of San Diego Reservoir is 20 minutes' drive away from this hotel. Tijuana Slough National Wildlife Refuge is 13 miles away.